President Takes Anti Malarial - Is Dettol Next?

[Peter Pedant]

The President cleared the room when he admitted taking hydroxychloroquine.
He had also found a doctor to prescribe it

and MY question is : if a relative did that and died - would you complain to the authorities ( GMC and courts here ) that the doctor had NOT acted in the patients ( your relative that is!) best interests and should pay you ( the estate ) much moolah and lose his licence

Note to help posters - hydroxyChlor does NOT have a licence to be used in warding off covid

[Peter Pedant]

// Seems like everybody wants it now...Ooo Errr Missus.//
To see if it has any prophylactic effect ( as it is used for malaria). It has to be a randomised controlled trial ( see Gaudret - he excluded the ones that died) - and in order to do that ...... there has to be equipoise - that the possible benefits are near the possible side effects. and I wd be happy to argue we dont have one of those.

consent for recruiting into the trial is gonna be fun - would the results of the trial be influenced by the nmber of reasoned refusals to take part?

//‘ However, evidence regarding its effects in patients is limited.’ //
Yep. No one said it wasn't.
Nope I think you will find someone in the White House hyping it.
but hey this is AB - you read one thing one day and the exact opposite the next!

[Spicerack]

At least posts that mention* HCQ aren't being removed from here now.
*Unless you claimed DT called it a miracle cure and it was killing everyone who took it.
Just shows the folly of censoring non-consensus views.

[Peter Pedant]

// DT called it a miracle cure//
um no we have been told categorically ( no dissent!(*) he didnt

Just shows the folly of censoring non-consensus views
erm no I dont think it does - "I think it is lawful to go to bed with small children and dogs" is a non consensus view that shd be given minimal exposure (IMO)

(*) for fear of generating whiney complaints from half of AB

Brazil has gone mad innit? - they are demanding chloroquine from Jair Bolsonaro to treat victims

[Spicerack]

Stupid argument, Pierre. Reducto Absurdium.
Giordano Bruno was burnt at the stake for claiming the Earth orbited the Sun.
You supplied the matches.

[Spicerack]

Anyway, your children and dogs analogy doesn't fly. It's just plain wrong unless you know a country where it is legal.

[douglas9401]

The 'children' one's easy enough.

[Spicerack]

Yes, but they don't like dogs, Douglas.

[xstitcher]

The Americans don’t complain to the authorities, they sue them!

[xstitcher]

It’s been suggested that Trump isn’t taking it, he’s just saying that he is. That’s one of his nasty little tricks to deflect from what is really going on from the mess his complete lack of leadership has created

[tomus42]

//It’s been suggested that Trump isn’t taking it, he’s just saying that he is. //

I did wonder about that when he said it. I couldn't see him knowingly doing anything to himself that was medically recognised as potentially dangerous. Except overeating, which he obviously has been doing.

[Peter Pedant]

the commentators are looking at the how and why
as well as the text - and noticed a little smile
BUT it caused a shock on a day when he wanted them to listen to something else ( stock market rising 900 I think)

altho some on this thread have distinguished prescribe ( bit of paper from a doc ) and administer ( swallow ) he did use the word take and not been prescribed
and I dont think the doctor would own up to prescribing it unless he knew the patient was taking it
Some talk about taking it for seven days to cover his valets covid

[Peter Pedant]

no one reads this anymore - BUT
today - 26 May 20 - chloroquine has been abandoned in one trial but NOT the one announced a few days ago

The abandoned trial was a look back exercise ( cue all the disadvantages especially bias and lack of randomisation and lack of rigour) which found no advantage from adding it in - to whatever else was being used
the evidence from this kind of trial is rated as 'weak'

[Spicerack]

Just to be clear, are you talking about Chloroquine (non-prescription) or Hydroxychloroquine (prescription) Only you seem to keep getting them muddled up. (accidentally :-))

[xstitcher]

Does it matter really what that idiot says he’s taking. It’s all lies. How do I know that he’s lying.....his mouth is flapping.

[Spicerack]

My God, you're a nasty old piece of work, ain't you.

[Spicerack]

Did it sound like I was asking you a question?

[youngmafbog]

Most anti-Trumpers are Spice. If he found a cure for Cancer they would find something to complain about. Must be something sadly missing in their little existence to be so angry all the time, often about someone who is really nothing to do with them.

[Spicerack]

They're all such dumb little critters, aren't they. They must love the way politics has been working for the last 30 years, making the rich, richer & the rest of us poorer. Perhaps they're all 1%ers who want to return to the status quo.

[Peter Pedant]

.


;


,
.

.Just to be clear, are you talking about Chloroquine (non-prescription) or Hydroxychloroquine (prescription) Only you seem to keep getting them muddled up. (accidentally :-))

HO-chlor. I am talking about that
You have taken a point as very important when it is not.
The difference is a hydroxyl group - peanuts. About the same as Pen-G and Pen - V and much smaller than the difference between Pen-G and amp.

take it from me - I have a degree in this or.... read this
Hydroxychloroquine, a less toxic derivative of chloroquine, is ...www.nature.com › cell discovery › correspondence
18 Mar 2020 - Vero E6 cells were treated with different doses of either compound or with PBS in the controls for 1 h and then infected with SARS-CoV-2 blah blahblah etc

BOTH increase the QTc interval - see here
https://pubmed.ncbi.nlm.nih.gov/18078640/

and no to answer my own question - I wd not allow a relation to take it unless they had malaria - on the grounds that we are all over 70 and a lot of us are fibrillating and it is a known dangerous drug

( you can spicey - I dont mind)

[Peter Pedant]

Ladies - I will include TTT and myself in that
this is an evidence based thread - can we veer away from phrases like
" you lying batch! you were lying about hydrocksy-whatever - weren't you!"

and more: "I recognise that the hydroxy group does not relate to its therapeutic action and may be intended to lessen cardiac effects. It has not been shown to be safer - and the hydroxy group have been added to evade a patent"