You would be poisoned by the poison in it's body.... But you probably meant venomous spider. As any creatures swallowed alive they would fall into cataleptic state (would fell asleep) in a dark enviroment in your body, where the oxygen is deficient. Most likely it would be crushed by oesophagus first, though. But can it bite you? Well, if someone unlucky swallows a wasp that person would get in a sting or two, before it reaches the stomach and gets digested. Spiders have a softer body and therefore much greater chance to be crushed, they also move slower than wasps. Practically the only chance to bite you is in your mouth. If it goes in it is food. Still, as you probably swallow it with some other piece of food, and that object just MAY stop it from being crushed there is a theoretical chance for a bite. But if you live in environment where there are venomous spiders on a move the chance of geting a bite from the inside is times smaller than chance to get a bite from the outside.