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No best answer has yet been selected by lover. Once a best answer has been selected, it will be shown here.
For more on marking an answer as the "Best Answer", please visit our FAQ.It rather depends on the artist I think. If you had an original David Shepherd (wildlife artist) it's value would be increasing and the popularity of the prints would make the original even more valuable.
But there are signed prints out there of unknown artists and I suspect their work would become neither more nor less valuable. It's more a matter of what the buyer is prepared to pay. Good art finds its own level in the end.