I would think that is the cause of the problem - I took Simvastin first, then Pravastatin, and then Ezetimibe and each one caused severe lower back pain, and no pain killers worked. On my doctor's suggestion, I stopped taking the tablet for 2 weeks, then re-started it, and each time, the pain went within a couple of days and came back again. I now take no cholesterol medication, and never have the pain. Try "googling" simvastin and see how many people suffer muscle pain - this is a definite side effect.