Yes definitely, in the same way that certain cultures feel it's disrespectful to look you straight in the eye - to us, where eye contact is important, that looks shifty.
There is some much about cultural differences in the way we conduct ourselves, and so easy if we don't know them, to get the wrong end of the stick about the way someone is behaving. Don't show certain cultures the soles of your shoes - others find shaking hands or kissing either acceptable for both sexes, or not at all. Very easy to make a faux pas if one is not aware!