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Picato Ream
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has anyone used this new cream for keratosis?
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I can't assist you directly but the National Institute for Health and Clinical Excellence has published a report that suggests that it's effective in some cases.
Quote:
"In 4 phase III, double-blind, randomised, vehicle-gel controlled trials of patients with actinic keratosis, ingenol mebutate gel was associated with significantly higher rates of complete lesion clearance in the treatment area, compared with vehicle gel. In pooled analyses of these studies, the percentages of patients with complete clearance of lesions after treatment with ingenol mebutate gel were 42.2% (face/scalp studies) and 34.1% (trunk/extremities studies), compared with 3.7% and 4.7% respectively of patients receiving vehicle gel (p
Quote:
"In 4 phase III, double-blind, randomised, vehicle-gel controlled trials of patients with actinic keratosis, ingenol mebutate gel was associated with significantly higher rates of complete lesion clearance in the treatment area, compared with vehicle gel. In pooled analyses of these studies, the percentages of patients with complete clearance of lesions after treatment with ingenol mebutate gel were 42.2% (face/scalp studies) and 34.1% (trunk/extremities studies), compared with 3.7% and 4.7% respectively of patients receiving vehicle gel (p
Part of my post has disappeared!!!
Full quote:
"In 4 phase III, double-blind, randomised, vehicle-gel controlled trials of patients with actinic keratosis, ingenol mebutate gel was associated with significantly higher rates of complete lesion clearance in the treatment area, compared with vehicle gel. In pooled analyses of these studies, the percentages of patients with complete clearance of lesions after treatment with ingenol mebutate gel were 42.2% (face/scalp studies) and 34.1% (trunk/extremities studies), compared with 3.7% and 4.7% respectively of patients receiving vehicle gel (p
Full quote:
"In 4 phase III, double-blind, randomised, vehicle-gel controlled trials of patients with actinic keratosis, ingenol mebutate gel was associated with significantly higher rates of complete lesion clearance in the treatment area, compared with vehicle gel. In pooled analyses of these studies, the percentages of patients with complete clearance of lesions after treatment with ingenol mebutate gel were 42.2% (face/scalp studies) and 34.1% (trunk/extremities studies), compared with 3.7% and 4.7% respectively of patients receiving vehicle gel (p
Aaagh!!!!
It's done it again!!!!
The (tiny) missing last bit of the quote doesn't really matter. (It's only some statistical stuff).
The source is here:
https:/
As I read that, ingenol mebutate gel (= 'Picato') is wholly effective in over 40% of cases of keratosis on the face or scalp and in over a third of cases elsewhere on the body.
So, while it's by no means a 'guaranteed cure', it certainly seems to be worth a try.
It's done it again!!!!
The (tiny) missing last bit of the quote doesn't really matter. (It's only some statistical stuff).
The source is here:
https:/
As I read that, ingenol mebutate gel (= 'Picato') is wholly effective in over 40% of cases of keratosis on the face or scalp and in over a third of cases elsewhere on the body.
So, while it's by no means a 'guaranteed cure', it certainly seems to be worth a try.
A further quote from that link:
"The most common treatment-related adverse events reported in the phase III studies were skin responses at the site of application".
As I read that (as a total amateur) there is, indeed, some risk of an adverse reaction (but it's not stated how great that risk actually is - after all, almost any medical treatment, even taking Aspirin, carries some level of risk).
A further quote:
"Local decision makers will need to consider the place of ingenol mebutate gel alongside other available treatments for actinic keratosis".
I read that as saying "Ask your dermatologist for his/her opinion!"
A final quote:
" . . . adverse events and cosmetic outcomes varied, and more direct comparisons between treatments are needed to determine optimal therapeutic approaches"
I read that as "the jury is still out on this one!"
Time to speak to your dermatologist, perhaps?
"The most common treatment-related adverse events reported in the phase III studies were skin responses at the site of application".
As I read that (as a total amateur) there is, indeed, some risk of an adverse reaction (but it's not stated how great that risk actually is - after all, almost any medical treatment, even taking Aspirin, carries some level of risk).
A further quote:
"Local decision makers will need to consider the place of ingenol mebutate gel alongside other available treatments for actinic keratosis".
I read that as saying "Ask your dermatologist for his/her opinion!"
A final quote:
" . . . adverse events and cosmetic outcomes varied, and more direct comparisons between treatments are needed to determine optimal therapeutic approaches"
I read that as "the jury is still out on this one!"
Time to speak to your dermatologist, perhaps?
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