If you've never done this kind of work before, I suggest you try to get a temporary administrative job, perhaps doing a Personal assistant holiday temp role.. I assume you have excellent I.T. skills because you will undoubtedly need to know your way around a computer. Being a personal assistant is not just about being tidy and organised. It's about knowing how to control somebody's office, liaise with their contacts (so lots of interpersonal skills needed for those difficult people you have to persuade to do things they don't want to do), and find your way about doing all kinds of unexpected tasks, many of which will seem way beyond your job description. Perhaps if you start in a small organisation where you're expected to be a "jack of all trades" you may get some kind of idea of what might be expected, but you will need to do the small tasks competently and with initiative to develop the confidence to take on bigger responsibilities and all the tasks which are thrown at you. Why not talk to a recruitment agency and see if they have any openings for you?