This is a tricky one. Face creams containing AHA's and similar fruit acid ingredients can help, but long term use may cause damage to the skin structure. Moisturisers will help the appearance. Best thing all round though is a balanced diet, never smoke and do not sunbathe.
I think 'wrinkles' around the mouth are attractive - they call them laughter lines, and it shows you know how to enjoy life! Someone did ask Mick Jagger about his 'wrinkles' and Mick confirmed that they were, indeed, his laughter lines. The questioner advised Mr Jagger that "Nothing's that funny!" Mr Jagger's response is unrecorded!