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In people with sickle cell anaemia and to a lesser extent sickle cell trait, the key feature is a change in the shape and flexibility of the red blood cells.
Very often people with SCA can have a low grade chronic anaemia, which is not a good thing to have preoperatively.
This deformity in the red cells can lead to a range of acute and chronic crises. Key factors in this deformity of the red cells are hypoxia, acidosis and low core body temperture. Sickling of the red cells can lead to various crises, for example vaso occlusive disease, which in turn can cause organ damage, cerebrovascular events, or musculoskeletal pain etc.
Anaesthesia during surgery can be a cause hypoxia, acidosis and low core body temperature if not monitored very carefully.
Very often people with SCA can have a low grade chronic anaemia, which is not a good thing to have preoperatively.
This deformity in the red cells can lead to a range of acute and chronic crises. Key factors in this deformity of the red cells are hypoxia, acidosis and low core body temperture. Sickling of the red cells can lead to various crises, for example vaso occlusive disease, which in turn can cause organ damage, cerebrovascular events, or musculoskeletal pain etc.
Anaesthesia during surgery can be a cause hypoxia, acidosis and low core body temperature if not monitored very carefully.
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