i rarely, if ever, fry off meat first. i know it is the 'done thing' but ,especially in a slow cooker, makes more work for yourself. just bung it all in and switch it on. nothing can burn because of all the liquid in it, and the meat comes out sooo tender. if you buy lean cuts of meat there's not a lot of fat that comes out, and in any case, you do need some fat for the taste. i would use hot stock, rather than cold.
some people swear by the george foreman grills, and rave about all the 'fat' that comes out of food. that 'fat' is what keeps it moist and flavourful, the george foreman turns food into cardboard.
it's trial and error really, boils down (pardon the pun) to what the individual likes.