Hello ilove ........... I don't think I've ever built, or renovated a house that didn't have at least one Velux in it ........... usually about twelve!
I've never done the maths, but I would guess that light from above (Velux) is possibly equivalent to maybe four or five conventional (wall-fitted) windows.
Facing a road, I wouldn't even bother with a window (it would have to be "blinded" all the time anyway ......) but that's a personal preference.
Depending on the dimensions of the room .......... one large, or two smaller roof windows set low down the roof slope ie sitting on the point where the wall meets the ceiling.
Also, I would avoid the "flat" ceiling, and "vault" it ....... ie ceiling slopey, attached to the underside of the roof rafters. Dramatic effect, and makes the room appear larger.
East facing? ....... morning sun through the Velux ....... :o)))
Also, as they say, other makes are available (cheaper too) ........
http://www.loftshop.co.uk/products.asp?catID=1