If the insulation material is a mineral (rockwool, glasswool, etc.) then the answer is almost certainly no because these materials are totally inert. There were voices about many years ago to the effect that injected foam might be suspect in this regard but to my knowledge it was never proven and it remains in use today. In fact, I live in a property insulated with injercted foam and none of my family appear to suffer from anything that could be attributed to the foam insulation. Our insulation was injected some 25 years ago. Any substances that are given off were only noticeable when the foam was setting but within a week they were not detectable and after that there would only be traces left, if any at all. There is an insulation bureau which answers queries - check with your local Citizens Advice Bureau for their number, or look on the Net.