I loathe Richard Littlejohn. Sincerely, deeply loathe him. In my opinion, he is one of the nastiest, most venomous and destructive columnists in the English language.
I also loathe what he wrote about Miss Meadows. I can't say I have any sympathy with the idea that the set-up has any kind of corrosive effect on children's 'innocence' (even ignoring the fact that most children are not anywhere near as innocent as Littlejohn seems to think they are). The school had no problem with it - the only person, apparently, who did was Littlejohn and presumably some of his readers. It would personally delight me for Littlejohn's career to be torpedoed and sunk.
Having said that, however, I can't bring myself to believe that there's yet sufficient evidence for such action to be taken. Littlejohn did not break the law in his original article, and there simply isn't conclusive enough evidence to suggest that had he not written it, Miss Meadows would still be alive. So, based on the evidence available at this point (which if I'm honest I'm not sure will change all that much), no - he should not be forced to resign.
This doesn't make his original article any less shameful a piece of cynical and manipulative gutter journalism, however.