The enduring popularity of Sherlock Holmes has led to many stage and cinematic adaptations of Conan Doyle's work. The Guinness World Records has consistently listed him as the "most portrayed movie character" with 75 actors playing the part in over 211 films. - wiki
Matt Smith is the eleventh actor to play the Doctor. Peter Cushing played Dr. Who in two 1960s films (but they aren't part of the TV series). There were various stunt men a stand-ins, but they would only appear briefly.
Jo Warne played the original Peggy Mitchell in the BBC soap opera EastEnders, making her first appearance on 30 April 1991. She appeared in ten EastEnders episodes between April and July 1991, as part of Sam and Ricky's teen elopement storyline. Barbara Windsor later took on the full-time role of Peggy Mitchell.
Guiness Book of Movie Facts and Feats has Sherlock Holmes: " The character most often portrayed on screen since the inception of the story film has been Sherlock Holmes, the master detective created by Sir Arthur Conan Doyle (1859-1930), who has been played by 72 actors," ...