Unless some diabolical engineer has been working overtime, my assunption is the threading works the same way in the U.K. as it does here in the U.S.
So, regardless of your or the bolt/nut orientation it loosens to the left or counterclockwise and tightens to the right or clockwise (not unlike politics, come to think of it).
There have been, historically, some few, very few alternatives to this rule. Some American made cars has lug bolts (holding on the wheels and tires to the axle) that operated exactly opposite, the belief being the rotation of the wheel while driving would help assure they were always tight. Additionally, some natural gas and propane fittings worked opposite for some reason. Here in the U.S., small propane tanks used to power barbeques were equipped with 'backward" threads, but most of those have been replaced just in the last few years...