Do You Agree That Antibiotic Resistance Are Good Examples Of Evolution In Action?
Bacteria & viruses soon become adapted to vaccines & antiviral drugs (or antibiotics for bacterium), as viruses & bacteria can mutate (& evolve) very rapidly.
These are examples of everyday evolution in action, since creatures with DNA evolved into various species (around 4 billion years ago) from primordial soup of amino acids & DNA bases.
Evolution is a fact of life, not merely theoretical speculation. Evolution & survival of the fittest for a habitat can be perceptible within days, like for antibiotic resistance. Drug resistance is due to mutation of organisms (like bacteria) to become more fit to pass on their genetic profiles to their offspring.
Those organisms that inadvertently evolved with ‘advantages’ characteristics for the specific niche they live in will produce more offspring. Antibiotic resistant bacterium are adapted to live & reproduce in environment of certain antibiotics.
Nature are hardy, even survival in deserts, polar ice caps at -50 C, hot boiling volcanic undersea vents are possible by mutation & evolution of the fittest through millions of years.
There should be adequate funding (by government, public & private organisations, etc) given to constantly develop new types of antibiotics, as bacterium & viruses evolve antibiotic resistance.
There are newer types of antibiotics are often administered intravenously in ITU/ICU (others are in development by pharmaceutical companies) – antibiotics like Clindamycin, Primaquine, Pentamidine, Trimetrexate, Dapsone, Atovaquone, Cefuroxime, Gentamicin, Teicoplanin, Clarithromycin, Tazocin, Ciprofloxacin, Ceftazidime, Vancomycin.
Mechanisms of current antibiotics includes:#
1. Antibiotics like Β-lactam antibiotics (like penicillin’s and cephalosporins) inhibit the synthesis of bactericidal effects by inhibition of enzymes needed for bacterial cell wall synthesis,
2. Sulphonamides antibiotics are a structural analogue of PABA & inhibit folate biosynthesis. PABA is required by bacteria, but not by humans, for folate biosynthesis. Human get their folate from the food they eat.
3. Antibiotics like tetracycline is selectively taken up bacteria and competes with the binding of tRNA to mRNA – hence interferes with during protein synthesises in bacterial ribosomes.
Anti-virals often act by suppressing reproduction of viruses RNA in host cells & budding off of new viruses from infected host cells.
Vaccine has eliminated smallpox, as well as at the threshold off eliminating polio, etc from the earth. Vaccines that are effective against the deadly disease of Ebola, AIDS, etc are being developed.