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Times Jumbo Cryptic 1021

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sam ledgard | 12:05 Mon 11th Feb 2013 | Crosswords
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Last one: 20d. Protein, one very much unknown, with unknown mass and energy.
I have I-O-E-E. I've tried isozeme and such, but can't confirm. Any suggestions please?
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20d Isozyme - 'i' (one) + 'so' (very much) + 'z y' (unknowns) + 'e(nergy)'
I somEZe . . . . 1 + some, E for Energy, Z unknown
. . . azpologies for typo. LK is correct
Apologies, I omitted 'm(ass)'...
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Thanks to all. Kicking myself because didn't spot I'd got anagram wrong in intersecting light, thus rejecting isozyme as answer.

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Times Jumbo Cryptic 1021

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