Ft 15650

[barnaclebill58]

Totally stuck -this will help please.
5a European city left in good heart (6)
21a I'm furious about opening of trade, I tell you! D?????
11d Top wizard pocketing grand (4)
18d Lover given easy opening (8)

[aelmpvw]

5a oporto

[Captain2]

21 Dammit - anagram of I'm mad + t(rade)

[Lie-in King]

5a Oporto - 'port' (left, in) '(g)oo(d)' (heart)
21a Dammit - I'm mad (about) + 't(rade)' (opening)
11d Acme (top) - 'ace' (wizard, pocketing) 'M' (1,000; grand)
18d Fan-light

[henlowgirl]

11 d acme

[barnaclebill58]

Thanks all -I was way off. Was thinking of l for left and therefore cities with an "l" in them and g for grand .