37ac- the main fact about ecstasy (5) - G???T
49ac- housework remains on the nettle tree (4,3) - ??O? A?H - hoop ash ? why?
23d- for king with glove on (3,6) - T?M ???T?N - tom kitten?
46d - top cyclist on motorbike (7) - ???R?E?
Some may be the dogs or cats theme in this crossword
TIA and Merry Christmas to one and all!!
HH