10a. To be blunt, a clue here could seem futile ??Y?T?E?S first letter could be a P. 13d. Low joint,technically speaking,where a star has a slug, being fuddled ?s???g???s (I think the "g" is right assuming 21a is soul searching 22d type of carp,we hear lay filleted and, in this way,shrinking c???y
thanks Lie-in King .. The Y was a faux-pas ! the 3 lettered clue for which I put "TRY" said "Three-point endeavour,say".. I realise it should be TRI. Cheers.
My medical dictionary didn't show astragalus even though I'd tried the anagram you stated...should've paid more attention in Biology !