Awake and aware both fit so I emailed Chris Feetenby. Here is his very quick, but not quite definitive response.
Thanks for your email. I don't do the crossword for YOU but I will pass your query on. I would have thought that both words answer the clue as it stands and will recommend that either be accepted, although the final decision will not be mine. Best wishes, Chris
Well, I think that in such a situation they should accept either answer. We are not mind-readers so don't know which one the compiler expected, but both of them, in my opinion, are valid answers then they should both be accepted.
If anyone has subscribed to this question - here's an update
Dear Eddie,
Thank you for your e-mail regarding this Sunday's YOU crossword. I agree that both 'aware' and 'awake' should be accepted as correct answers for 22 across and have informed the department that checks the crosswords to do this.
Thank you for your interest in the YOU crossword. I do hope that you continue to enjoy it in the future.
Best wishes,
Liz Murray