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Spectator 1897

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Helveticus | 22:07 Mon 19th Jan 2009 | Crosswords
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I'm stumped by 18d: Mashed on ecstasy, be unfit for another drug. (10)
I have ?u?o?e???e

Are there any pharmacologists or others out there who can help?

Thanks in advance.
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bufotenine
Bufotenine: anagram of 'on e(cstasy) be unfit'.

No pharmacologist me.
bufotenine

anag of ON (E)cstasy BE UNFIT
definition:

A poisonous hallucinogenic alkaloid obtained from the skin glands of toads of the genus Bufo or from some mushrooms.

http://animals.howstuffworks.com/amphibians/ha llucinogenic-frog.htm/printable
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Grateful thanks to all the above!

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