D.T G.K 10 November

[Hoffy]

Spent all day and am defeated with this one. Help please with 8d. Doctor meant to replace curative substance(10)
15d. Mysterious clique entered into by one lady or another(10)
21a. Appropriate international body first out of condition.
Confirmation please that 14a is mariuhana (Lady got round spanish man for drug)
Thank to any who might reply

[ace bt]

medicament

jacqueline
unfit
marijuana

[Hoffy]

Thank you so much. All my problems were because I misspelt marijuana.

[chasnoel]

am mystified by this question. I am sitting with the Saturday's D T G K puzzle on my lap and there are no such questions. Where do they come from ? Is there another paper apart from the Daily Telegraph which has the initials DT?