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HIV reverse transcriptase

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flano | 16:17 Thu 26th May 2005 | Science
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Anybody know anything about DNA who could tell me Could HIV be erradicated if we removed the protein reverse transcriptase? Has this already been tried or is it impossible?

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No it is an idea which will get up and run

As a protein target it is rather a good one as it is a protein that does not occur in mammal cells and so should be specific. toxic effects hould be low

Actually it is not a very efficient protein and the mistake rate in transcription aids (haha!) the generation of diversity and mutation rate. HIV's rate of mutation is high.

Drugs have been developed for this - of which I cannot remember one - ddI ? and they work quite well.

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HIV reverse transcriptase

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