The cemistry of an element is dictated by the number of electrons and therefore protons it contains. Each element has a different number of each. However the neuclius of an atom also contains nutral nutrons. Elements may contain different number of neutrons but have the (essencially) same chemical properties, these are call isotopes. Only a few elemts have only one natrually occouring isotope, most have atlease 2 or 3. Some isotopes of radioactive elements are more easily broken up during fission and are therefore important in power generation and bomb making. For Uranium the most common is U238 (99.275%), but U235(0.72%) is the important one for most fission applications, there is also a natrually occouring U234 (<0.005%). In some reactors U233 is also produces by neuclear reactions, this can also be used in fission applications.
Another commonly heared about isotope and isotope of hydrogen (1 proton, 1 electon, 0 neutrons) is deuterium (1 proton, 1 electon, 1 neutrons), which is not radio active and D2O is called heavy water. The other isotope of hydrogen is Tritium (1 proton, 1 electon, 2 neutrons) but this has to be made by neutron bombardment of deuterium and is radioactive.
I hope this is understandable as I have assumend you know about protons, neutrons and electrons......