atherosclerosis/ thrombi

[mollykins]

Next week in biology, we're having a mastermind quiz. We had to pick the part of the topic that we struggled with the most and revise it, to be asked questions on.

The thing i find hardest and what i get mixed up with is the formation of atheromas, leading to atherosclerosis and the formation of thrombi, but what questions could they ask me?

Any ideas?

[squarebear]

Considering you didn't know who to phone up to ask why your school was closed, I personally wouldn't bother with it.

[mollykins]

What a rude an unrelevant answer!

[mollykins]

You don't even know if it is the same school and what was the point in making that comment anyway?

[squarebear]

It doesn't matter if it's the same school or not, the principle remains the same.

My point in posting is that you don't appear to have a great deal of common sense and now you ask about, "the formation of atheromas, leading to atherosclerosis and the formation of thrombi"

I would suggest a more simple topic for you to study if you have no idea what questions they could possibly ask you.

[ttfn]

Hi molls. Have you tried googling this or looking on NHS direct - anywhere there may be an FAQ section? Have a go and see what you can find :o)

[NazNomad]

http://en.wikipedia.org/wiki/Atheroma

http://en.wikipedia.org/wiki/Thrombi

[mollykins]

There's a couple of pages on it in the textbook, but only really about the stages of their formation, I was wondering if anyone else knew anything else they might ask me.

[Sqad]

Questions that are relevant:
1) What is Atheroma
2) Where is Atheroma commonly deposited
3) What predisposes to Atheroma.
4) What may be the sequelae of Atheromatous plaques.
5) What is a thrombus.
6) What is the difference between a thrombus and an embolus.
7) Is there a connection between high blood cholesterol and heart disease.
8) What are HDLs and LDL´s

They should cover any eventual questions.

Good luck.

[mollykins]

Thanks squad, pardon my ignorance but what the heck is number 4 on about? and i'm not sure if embolus is covered in the exam, but I remember that word from somewhere . . . . <goes to investigate> . . . .

[Sqad]

sequelae.....consequence of......can lead to........what may follow.

[mollykins]

1) A build up of plaquey stuff made from calcium salts and crud.

2) is it atheromas that are arteries only and thrombi that can be any vessel . . .

3) (I think I know what you're asking) if you lead an unhelathy lifestyle such as eating a diet high in LDLs, salt and alcohol aswell as smoking and not doing much exercise.


5) in laymans terms, a blood clot.

7) well LDLs are bad and HDLs 'mop' the LDLs up from the blood to the (liver?). if you have too much LDL in your diet, (does it thicken your blood?) so thrombi and atherosclerosis are more likely to form which may blcok your whole vessel leading to a myocardial infarction . . .

8) low/ high density lipoproteins, two kinds of cholesterols, there's also very-low-density-lipoporteins aswell.

[Sqad]

1) More or less correct

2)Correct and on heart valves...aortic and mitral valves in particular

3) Correct + of course diabetes mellitis

5) Correct.

7) Correct

8) Correct.

Well done molly.

[mollykins]

Yay, thanks squad.

4) I get a bit muddled with it and thrombi. 1. damage to artery wall endothelium from high blood pressure. 2. something to do with white blood cells and cholesterol leaving or entering the artery wall. 3. an atheroma then forms which builds up calcium salts and fibrey stuff which combine to form plaque. 4. this blocks the artery, raising BP even more and positive feedback of it getting worse happens.

[Sqad]

molly....excellent

4) Atheromatous plaque,,,,,,coronary artery,,,,obstruction>>>>>>death of heart muscle (ischaemia)>>>>>>heart attack>>>>>cardiac arrhythmias >>>>>>> ventricular fibrillation>>>>>>>death.

Cerebral artery......blockage>>>>>ischaemia (blockage)>>>>>>>stroke.

Limb artery>>>>>blockage>>>>>>>gangrene>>>>>>>>amp
utation.

[mollykins]

and ischaemic means 'without blood' because something such as a vessel has been blocked so blood can't be delivered somewhere . . :)

[mollykins]

well to the person whom it was happening it would be a :(

[Sqad]

Molly...spot on.