Only you can decide whether and how to mention your uncle.
I am sorry for your loss.
I would be careful, though.
I attended a wedding where the bride's sister had died of cancer a few months before and the Father of the Bride's speech was much more about the daughter he had lost to cancer than about the one that was getting married.
It certainly cast a blight on the proceedings with the Mother, widower and children of the dead sister all becoming quite upset.
Not what you want at your wedding and , sadly, almost all I can remember about that one.
It is a difficult one. If it was me I'd check with your uncle's widow and any children that they are not going to be too upset. It is very early days for them and they might prefer a 'day off' at your wedding.
I'd also ask your future wife what she thinks.
I hope whatever happens that all goes well for you and that you and your future wife have a long, happy and healthy life together.