When a PC first starts up it has no idea which devices contain an operating system such as Windows, and which device to "boot " from.
There could be an operating system on diskette (honestly), hard disk or CD or DVD.
So the PC looks on each of these devices, one at a time, trying to find a file that identifies itself as a "boot" volume.
If the PC cannot find any device with the "boot" file then you will get a message like you have got.
This may be for a number of reasons.
One reason may be that the "bios" in the PC has "lost" the device (so the PC does not even know the device, say hard drive, is even there).
Another reason may be that although the device, such as hard disk, is there, maybe the "boot" file has become corrupt or deleted so the PC is not able to boot from it.
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