This question has been coming up practically as long as the 747 has been in use for ferry flights. For the approach and landing test flights where the shuttle was air-launched from the back of the 747 the shuttle was mounted with a nose-up attitude, about 7 degrees I think. The 747 dived immediately prior to release and thanks to the shuttle's nose-up it was generating enough lift to pull away from the 747. Note this wasn't enough lift to "fly", just to fall more slowly than the 747. For the ferry flights the shuttle is mounted differently and provides almost no lift at all. I've seen an estimate of c1000 lb but don't know how accurate that is. The 747 is empty apart from fuel and crew and has a comfortable margin of power to carry the empty shuttle. It does require additional vertical tail surfaces, however, and suffers significant penalties in its range and altitude performance.