Seen all the main tourist attractions in Prague the castle, palace etc
Most places easy to walk to if you want to give your feet rest jump no a tram!
took a trip to Sedlec Ossuary outside Prague long bus trip when on a tour worth it though unbelieveable!
Wouldn't recommend the Communist museum, found it a bit boring but then again i didn't really know much about their history
If love art especially Art Nouveau visit the Mucha Museum
www.mucha.cz (One of my favourite artists)
There is a Dali exhibition in Wenceslas Square although i'm not sure if this is a permanent thing
useful website on events in October in Prague
http://www.pis.cz/en/prague/events/october/gal leries_and_exhibitions/searchresult=%22On+Wenc eslas+Square
Visit the tourist information place for what to see and do
probably be quite chilly in October i went in June
Enjoy!
if in doubt where any of the tourist places are just ask someone or show them where you are trying to go with a leaflet or map even if they can't speak english they try to help most are friendly!