Dt Prize 28,863

[what a twit]

4 down (5) Operatic heroine’s career’s beginning to take off M?M?C Imagine this is MIMIC but grateful for parse as to why.

[goodgoalie]

Mimi (La Boheme) + C

[Captain2]

Operatic heroine = MIMI + C(areer's beginning)

[bookbinder]

Mimi is the name of an opera heroine.
C = Career's beginning = first letter of career's.
To take off = to mimic.

[Lie-in King]

Mimi (lead in "La Boheme") + 'c(areer)' (beginning)

[what a twit]

Thanks everyone.

[dannyk13]

Mimi (heroine of La Boheme) + c(areer)