Yes- Phone Sky and tell them you want x amount of additonal mouses and remotes. A mouse sits on top of the 2nd 4rd or 4th TV and the extra handsets allow you to change channels without taking one remote all around the house. there's another bit that plugs in the back of your sky box - It's all very discreet.
Or get a wireless video sender. These send the picture from your sky box to the bedroom, for example, and the remote signal back the other way. Quality isn't brilliant, but it does do the job.
Google for 'video sender' - there are loads available.