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Thanks for your answers, it's interesting to see what gives people a tingle rush. It's strange, there have been several pieces of classical music mentioned, but having thought carefully about it there are very few classical pieces that make me shiver. (i have a large collection of classical CDs though) For me, it's mainly more modern music that causes shivers. I've thought of a few more; "Insomnia" by Faithless affects me big time, and an obvious choice would be the intro to "Shine On You Crazy Diamond" by Pink Floyd. Slimjim's answer got me thinking - quite a few tunes associated with sporting events have a similar effect. Jerusalem was used not long ago, and "Abide With Me" when played on FA Cup final day always gets a response. I'm in total agreement with 5029 and froggequene about The Power Of Love. That is a very emotive song. URU2, i can't honestly say i know the Mazzy Star tune, but Teardrop is definately a good call. "Angel", also by Massive Attack is a contender too. mikewith's Johnny Kidd & The Pirates track is a real tingler, but i'm not sure about Two Little Boys! I'm a bit shocked not to get more medical insight into what causes it - perhaps i should ask in "Body & Soul", might get a better explanation there. I'm pretty sure it has something to do with memories causing the brain to release chemicals, but i'm not a medical man so i don't know which chemicals! Oh well, happy tingling, and thanks again. =)