The synthesised drugs mdma and mma were discovered trying to find appetite suppressants to use as diet pills. Hence I radically lost weight when I was taking them and at one stage I had a minor stroke from staying awake for very long periods of time (though that was mainly due to amphetime, ecstacy also played a part.) the most I took in a night was 14 when I was 18 years old and I'd only been taking them for about 8 or 9 months by the time I could tolerate that amount, and they were good pills too, triangular mitsubishi's, really chunky blighters. When I had the stroke I had been awake for 13 days. Luckily the only lasting side effect I've noticed (so far) as altruism but I think everyone should have a bit more of that.