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Non-competative Inhibition

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Shannc022 | 23:14 Wed 14th Jan 2009 | Science
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Can a non-competative inhibitor allow a different substrate to bind to the active site of an enzyme?
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Avatar Image Peter Pedant
No I dont think it can, because,

and NC I bonds with a covalent bond and this has to be near the binding site.

[could it bind somewhere near and just distort the site ie allosterically}

and so if it is on the site and covalently,
then it will stop the binding of the target AND all related mols.
22:00 Thu 15th Jan 2009
Avatar Image theprof
It's not impossible. I suggest you look up allosteric inhibition for further information.
02:32 Sat 17th Jan 2009
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Avatar Image theprof
I'm afraid not. I tend to confine myself to sensible reading as I'm of the opinion that such publications can rot the brain. Tell me, do you know a reader?
02:40 Sat 17th Jan 2009
Avatar Image Ice.Maiden
Probably, noknow, probably. Even intelligent people need a bit of a laugh now and again.
02:40 Sat 17th Jan 2009
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Avatar Image theprof
Ah i knew it! You're one oneself no.knowledge!
02:44 Sat 17th Jan 2009
Avatar Image theprof
Oops, that should have been:

Ah I knew it! You're one yourself no.knowledge!
02:49 Sat 17th Jan 2009
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Avatar Image Jan1957
Beam me up Scotty
02:55 Sat 17th Jan 2009
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Avatar Image Jan1957
It's too late Captain, they're going to blow!
02:57 Sat 17th Jan 2009
Avatar Image Ice.Maiden
I don't think they're going to be very happy with you, noknow! S posted a serious question. : (
03:06 Sat 17th Jan 2009
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Avatar Image Ice.Maiden
Lol - tell you what hun, I'll send all my old New Scientist mags to you, and by the time you've waded through them all - you'll be able to come on here and off some amazing answers!!! : )
03:15 Sat 17th Jan 2009

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