Well, outside of the aforementioned jack rabbit there are the occasional Desert tortises... but don't miss the world's tallest thermometer... the thermometer is 134 feet high -- and is in Baker, CA., and of course,
Primm, NV just across the border. (Seen here:
http://www.primmvalleyresorts.com/). It's really an oasis just before the onset of the real desert. I haven't been there in a while, but it even had a pretty cool roller-coaster of the old style.
Plenty of places to fuel until Barstow, then I'd make sure I had a full tank... but even then there are other, shall we say, unusual places to stop for gas, like
Roy's in Amboy, but that's kinda out of the way. For the truly adventurous, one could always drive through Death Valley or the Mojave National Preserve... but if you do emulate the jack rabbit... Again, welcome!