Ok, I have a few, some I think I know but then other clues don't fit, so I'm going to put ALL the questions to you and see what answers you all come up with.
2 Down - Radical transformation (3, 4) ??? CHANGE (sex change?)
10 Across - Yes-Man (7) C???L?R (the 3rd letter of this is the 3rd letter of 2 Down)
15 Down - Be horizontal (3) L?? (Lay or Lie?)
19 Down - Disputes (4) ??W? (Rows?)
18 Across - Shake, quake (6) ???VER (the 2nd letter here is the FIRST of 19D & the 3rd letter here is the LAST of 15D!! I'm having probs making them all fit).