Yip, I've used it and I was very happy with it. I never had any of the associated problems and I lost a stone and a half which I've managed to keep off. I didn't have to make huge changes to my diet - I just opted for the lower fat versions of things (the threat of accidents is a much stronger incentive to cut out fat than will power). I didn't have to starve myself and I wasn't constantly craving things I couldn't have. I didn't notice much weight loss at first although I was losing it gradually according to the scales, but it became obvious quite suddenly and I certainly feel a lot better about myself for losing the weight. For all I cut down on my fat intake, I wouldn't have lost as much just by doing that alone, the tablets definitely made a difference and I would say, if your Dr has recommended them, give them a go but be patient :)