Well I wish you the best of luck.
First the most important aspect of business is not to put too many eggs in one basket. Just like savings where you diversify. What I'm saying is don't use one wholesaler for almost everything.
Second, being in the wholesale end for 12 yrs. and having many friends at the retail side, I can say you have to put some trust in your wholesalers as they will be a big part of your business. ( I always tell my customers "I'm not pushing merchandise you can't sell, the only way I make money is if you make money).
Last but not least make sure your interests are also the general public interests. i.e I am into weird stuff and don't understand why anyone buys some of my product yet it sells. If I were a retailer I'd be in the pits.
Good Luck once again,
Enjoy your business!