Testicular Tumour - Blood Test Results

[oldhamfan]

Good afternoon. In relation to a testicular tumour not yet diagnosed as cancer, what do the following blood results denote?

HCG 12
AFP 2
LDH 227

Does the above shed any light on diagnosis? The subject is a 32 year old male with Seminoma in the family history.

Thanks in advance.

[Sqad]

THis is a rather specialised question and you will need ABERS Lazygun or slaney to give you expert advice.

The figures thatvtounhave illustrated are markers of the tumour and are best used as response to treatment rather than a diagnostic tool

The AFP is certainly normal as is the HVS and LDH.

The diagnosis will be made on biopsy.

LazyGun or Slaney should be along later.

[oldhamfan]

Thanks for your help so far.

[LazyGun]

Assuming the values as shown are the common reference range values, then I would say the HcG level is a tad high (NR Adult Male 0-5 mu/ml), AFP looks normal (NR Adult 0- 40 odd ng/ml), and the LDH looks normal (NR Adult 100-260 iu/L ?).

Difficult to draw any firm conclusions from those results on the nature/stage of a tumour or cancer or otherwise. If memory servers,Seminoma usually has a normal AFP anyway, and HcG may sometimes be elevated, sometimes not, across a range of cancers /tumours.

For those patients diagnosed with testicular cancer, 40% of the time they would have a normal AFP and HcG anyway. Biopsy, physical examination, maybe ultrasound are the diagnostic tools - lab tests more confirmatory than anything else.

[oldhamfan]

Thanks very much.

As I understood it, only histology can provide diagnosis but pending that, blood can have some giveaway signs and the waiting is nerve wracking, made worse by the time of year.

Many thanks for your detailed reply.

[oldhamfan]

Diagnosed yesterday as Seninoma, thanks for your assistance.