What a swine today! The theme is nuclear physics (in which we are all well-versed). I am in the unenviable position of being stuck!
9a Clergyman into Creation with clay as result at 16A 25 24 is best recorded.
?b?u?a?e?? (10)
The answer to 16A 25 24 is Large Hadron Collider. The only word I can get to fit is OBDURATELY, but if that is correct the wordplay defeats me. I can see most of "curate" (clergyman) in there but precious little else.