Hi, I have been to San Diego and my sister lives in San Francisco! Some advice for you: If choosing Las Vegas, first read this Web page, it will tell you how long the drive from San Diego to Las Vegas takes and which driving route is ideal:
http://www.virtualtourist.com/f/p/5e2f/
Once
you are in Las Vegas, it's a relatively short trip to visit the Grand Canyon, which is one of the best places to visit in the U.S.! There is more to see there than one would think!! I personally would not recommend a drive to San Francisco, because it would take at least 8 hours (tiring!) and could take up to 10 if you run into rush-hour traffic around Los Angeles. However, the view is spectacular all along that route-- the Pacific Coast Highway-- so you could always drive on that for a few hours without going all the way to San Fran. Los Angeles is very close to San Diego, if that appeals to you.... And, honestly, you would have no trouble spending the entire 10 days in San Diego without a moment of boredom. The San Diego Zoo is one of the best in the USA! There are top-notch museums, animal parks, theme parks, etc., galore. Check out these two informative Websites to see what I mean!!!
http://gosanfran.miningco.com/cs/sandiego/
http://gosanfran.miningco.com/cs/sdmuseums/index.h
tm
Have
a wonderful trip!!!!