Daily Telegraph Toughie Thursday November 7Th 2013

[catsrcool]

27ac Cough needs fresh tissues with no end of resistance (6) t?s?i?
3dn Have a meal in German city (5) e?s?n= essen why?
6dn Try French art for example (5) e?s?y =essay why?
11ac Affirmative answers being found in heart of Harley Street (6) ??s?e? = yesses why?

[sedge47]

27a tussis
3d Essen is a German verb meaning to eat
6d ES as in 'tu es' (thou art}
11a esse means existence or being

[factor-fiction]

http://www.thefreedictionary.com/tussis
Anagram of Tissue minus the E

[dannyk13]

27a.Tussis (anagram of tissues - e)
3d.Essen (eat in German = essen)
6d.Essay ( French art= es +say)
11a,Yesses (being =esse in y s)

[factor-fiction]

and for 6d the 'say' comes from 'for example'

[catsrcool]

Thank you all