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No best answer has yet been selected by Shannontrae. Once a best answer has been selected, it will be shown here.
For more on marking an answer as the "Best Answer", please visit our FAQ.It is about 200 miles from London to Manchester so I do not see any way you are going to get there in one and a half hours.
As I see it you have three choices, Car, Train, Coach.
If you have a car, or can hire one, you are still talking over 3 hours to drive there, maybe nearer 4 with breaks.
National Coaches run coaches all over UK, but I guess it will take more than 4 hours with all the stops.
Or as Xollob says, train is 2 hours and 40 minutes, but it would be almost impossible to do there and back in a day, or if you could you would only have about 10 minutes in Manchester.
I would plan an overnight stay in Manchester, maybe 2.