6a, Prudish pair going to Seychelles island included (6). 10a, Leave work at the wrong time? (5-3). 21a, Before a doctor left half of preliminary statement (8). 17d, Overwhelm with work on...
39d, Gold coin with a depiction of St Michael killing a dragon, first used in France in 1340 and later introduced to England by Edward lV in 1465 (5) ?N?E?