It can affect bitch's that way.
My girl on her first season would not tolerate the car engine running - thankfully she grew out of it!
She probably wonders what is happening to her.
If she suddenly goes off her food/water and/or starts being sick and depressed/off her feet then get her to the vet as soon as possible as they can develop a condition called pyometra that is life threatening.
If you are really concerned then it may be worth a visit to the vet just to put your mind at rest.