16th century? I think that you'll find that should be 17th century!
Prints of his work aren't exactly expensive ;-)
http://tinyurl.com/23rs2t2
If you can spot a nice, cheap frame in a charity shop - perhaps containing a suitable size mount - (and, of course, assuming that you like the print enough to want to put it on your wall!) it's probably worth re-framing. If you love the print so much (irrespective of its financial value) that you're happy to spend money on professional framing it might also be worth getting it done. Otherwise don't bother.
Chris