If you are prescribed new medication and, the first time you take it, you get an upset stomach and generally don't feel good, do you stop taking that medication and go see your doc about an alternative, or do you persevere and see how it goes over subsequent days?
It depends on the medication. I take tramadol (100mg 4 times a day) and have been on them for several years, they still occasionally make me feel queasy if I take them on an empty stomach. I find the benefits far outweigh the down sides though so I keep taking them.