Hi, yes a few years ago I was going through a very bad patch and St. John's Wort definitely helped after a week or so. I also knew someone who depended on it for years (after her daughter was killed) once she'd come off the authorised doctor's medicaments and she had no side-effects either. I think that it is important to tell your doctor that you are taking it. I have read of people having problems with it, but not in my experience. I found it a gentle helper.