As ever isolated laboratory tests can be difficult to interpret without full clinical details and symptoms.
A high D-Dimer might suggest DVT/PE, but there are other causes.
I presume thrombosis has been excluded by duplex ultrasound, and or CT chest with contrast.
If there is a strong suspicion the ultrasound may need to be repeated in one week - all depends on something called the Wells score.
D-dimer can be raised in infection, and other conditions.
*Anecdote alert*
When I was in hospital three Christmases ago with pneumonia, someone was unwise enough to do a d-Dimer which was of course raised because of the infection. I had considerable difficulty to persuade them I had not got a PE as well.
To add insult to injury the anticoagulant referral form I was given had my name on the top even though I had been retired some years.